Author Correspondence author
Molecular Pathogens, 2024, Vol. 15, No. 4
Received: 16 May, 2024 Accepted: 22 Jun., 2024 Published: 08 Jul., 2024
Predatory bacteria have garnered increasing attention in pathogen control research due to their unique predatory mechanisms. This study provides an overview of the historical background of microbial predation and the discovery of predatory bacteria, focusing on the mechanisms of bacterial predation, including predator-prey cellular interactions and metabolic adaptations. Both in vitro and in vivo studies have demonstrated the significant effectiveness of these predatory bacteria in eliminating multidrug-resistant pathogens, particularly highlighting their potential in biofilm-related infections. Although predatory bacteria show promise for clinical applications, challenges such as prey resistance, environmental factors, and safety concerns still require further investigation and resolution. In the future, genetic engineering, applications in agriculture and veterinary medicine, and the integration with bioengineering and nanotechnology will pave new pathways for the application of predatory bacteria. This study aims to enhance the potential of predatory bacteria through these innovative approaches, ultimately providing a basis for their clinical use as therapeutic agents.
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