Bioinformatic Analysis of MYB Transcription Factors in Fusarium graminearum
Key Laboratory of Biopesticides and Chemical Biology, Ministry of Education, Fujian Agriculture and Forestry University, Fuzhou, 350002
Molecular Pathogens, 2020, Vol. 11, No. 1
Received: 07 Jul., 2020 Accepted: 07 Jul., 2020 Published: 10 Jul., 2020
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This article was first published in Molecular Plant Breeding in Chinese, and here was authorized to translate and publish the paper in English under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The bioinformatic method was used to analyze the 17 Fusarium graminearum MYB transcription factors (TFs) included in the fungal transcription factor database. Analysis of gene sequence and protein physical and chemical properties showed that the 17 F. graminearum MYB TFs differ in gene length, protein size, theoretical isoelectric point, total number of atoms, and instability index; Motif analysis and protein secondary and tertiary structure prediction found that these transcription factors contain 2 characteristic motifs, and that the protein structures are diverse, but all contain the MYB TF characteristic structure (helix-turn-helix (HTH)); Phylogenetic tree analysis showed that 17 F. graminearum MYB TFs of and 12 reported MYB TF3 from other species have evolved into two large clades. Among them, FgMYB03, FgMYB04, FgMYB05, FgMYB06, FgMYB10, FgMYB12 and FgMYB13 have close relationship with known animal, plant and fungal MYB TFs including c-MYB, ATMYB2, MoMyb1, FlbD and Pol5, which implied that they possibly share similar biological functions. These results provide a reference for further research on the biological function of F. graminearum MYB TFs and the feature of other fungal MYB TF family.
MYB transcription factors; F. graminearum; Bioinformatic analysis